Thursday, July 4, 2013

The Hazards of Working Nights: for breasts and beyond


The jury is still out whether Angelina's choice is brave or fearful, but the fact remains: having or not having the "bad" genes is not enough to develop or avoid developing breast cancer. As a matter of fact, only 5% to 10% of breast cancer cases result directly from inherited gene defects. Check it yourself, by using this decision tool developed in Stanford.  Even though for members of some families with BRCA mutations the risk may be as high as 80%, this could be because of environmental exposures and behavioral habits "running in the family". What are they?

Among the controllable risk factors are hormone therapy, birth control pills, drugs (like DES discontinued in the 70s), the use of alcohol (if 2 or more drinks per day), heavy smoking since early age, gaining weight after menopause, exercising less than 1-2 hours per week,  certain cosmetics and personal care products, pesticides (such as DDE), PCBs (polychlorinated biphenyls) and other environmental exposures.


One of such exposures is working at night. And Kristan Aronson's team from Queen's University showed that the risk is not limited to nurses, as in most previous studies.


The study examined over 1000 breast cancer cases vs about the same number of healthy cases, matched by age in Vancouver, British Columbia and Kingston, Ontario.  It found that breast cancer risk was twice higher with 30-plus years of night-shift work versus people that did not have night-shift jobs. The risk is more than three times higher for those working at nights in the health care field. But people working at nights or having rotating schedules for shorter duration of time seem to be unaffected.

Why would staying awake after dark for many years be hazardous to health? Perhaps because of the lack of Melatonin. This hormone is produced naturally by our brains when lights go out, to make us less alert and prepare us for sleep. The more daylight exposure versus night time darkness, the better. Melatonin might help the body in many different ways - for example, by downregulating some of the hormones influencing tumor growth or by exhibiting anti-oxidant and immuno-enhancing properties.
Night shifts are also associated with increased stress and a plethora of health conditions as seen from the number of sick leaves people take, periodontal index (measure of oral health), glucose tolerance, number of heart attacks and strokes, cases of IBS and internal cancers. Actually, night time work was shown to increase the risk of cancers even more than exposure to exhaust fumes.

But this is all statistics. Individual cases can certainly break the mold. Yet, it's summer, so let's make the most of natural light.

REFERENCES

Grundy A, Richardson H, Burstyn I, Lohrisch C, Sengupta SK, Lai AS, Lee D, Spinelli JJ, & Aronson KJ (2013). Increased risk of breast cancer associated with long-term shift work in Canada. Occupational and environmental medicine PMID: 23817841

Hansen J, Lassen CF Nested case-control study of night shift work and breast cancer risk among women in the Danish military Occup Environ Med 2012; DOI: 10.1136/oemed-2011-100240.

M S Wolff and A Weston. Breast cancer risk and environmental exposures. Environ Health Perspect. 1997 June; 105(Suppl 4): 891–896. PMCID: PMC1470027

Madigan MP, Ziegler RG, Benichou J, Byrne C, Hoover RN. Proportion of breast cancer cases in the United States explained by well-established risk factors. J Natl Cancer Inst. 1995 Nov 15;87(22):1681–1685.

79 comments:

  1. Just as one international college student with a scholarship grant I seriously could not have the funds for to hire a high-end writing services to post must write my essay for me in my opinion. Additionally the particular terrible ordeals regarding most of the guy students having a few web-sites were being deterrents. However last but not least I ran across this glorious services inside spending budget.

    ReplyDelete
  2. Among the controllable risk factors are hormone therapy, birth control pills, drugs (like DES discontinued in the 70s), the use of alcohol (if 2 or more drinks per day), heavy smoking since early age, gaining weight after menopause, exercising less than 1-2 hours per week, http://findmybud.com/

    ReplyDelete
  3. good is not available formally on Google Play store. mobdro ios the ability to find Mobdro on Google Play Store. best.

    ReplyDelete
  4. good that would certainly have given us access tutu app download Tutu application for android most likely to the TuTu app best.

    ReplyDelete
  5. Naturally supports a woman's health needs by replenishing your body's "good" bacteria to help you feel and live comfortably while acting as a natural yeast infection treatment . women health's website

    ReplyDelete
  6. All For One Home Health Care Inc. is a team of health care professionals who make your home an alternative to a hospital or nursing home stay. iv therapy

    ReplyDelete
  7. Trichophytic closure is a special technique used for the closure of the donor area. Using the technique makes the scar almost invisible and even aids the growth of hair from scar. This helps the surgeon to achieve a better aesthetic outcome of the surgery. Such an advanced technique is difficult to perfect and Dr.YV Rao has mastered it.
    recedinghairline.us

    ReplyDelete
  8. Some universities or colleges may have insurance plan offered to students. These insurance may not answer all your needs but you need to be meticulously considered it. www.smarthealthadvice.com

    ReplyDelete
  9. Many of the elderly have chronic conditions that overwhelm their daily activities or they get diseases repeatedly, which ultimately raises health insurance premiums.Smart Medigap Plans

    ReplyDelete
  10. A specialist was not only there to treat a patient, he was intended to help him remain healthy. Excessively numerous lights outside the house implied awful business for the specialist. urgent care near me

    ReplyDelete
  11. Neuropathy doesn't have to leave you in pain and dissatisfied with life. Taking control of your condition can be difficult, but it is worth it. Neuropathy treatments include: Types of neuropathy

    ReplyDelete
  12. In this day and age, when the worry of present day way of life is producing a bigger number of patients than effective people it is difficult to discover or distinguish where might you get great healthcare administrations. fungus key pro

    ReplyDelete
  13. The Hazards of Working Nights: for breasts and beyond nice title and post Expert Love Solution

    ReplyDelete
  14. But people working at nights or having rotating schedules for shorter duration of time seem to be unaffected.secondary focal hyperhidrosis

    ReplyDelete
  15. However, they will likewise be delighted to hear that herpes can be treated and controlled. mylastoutbreak.com

    ReplyDelete
  16. Angelina's choice is brave or fearful, but the fact remains: having or not having the "bad" genes is not enough to develop or avoid developing breast cancer. best posture corrector

    ReplyDelete
  17. The good cholesterol protect us from heart disease and stroke while the bad cholesterol does the exact opposite of exposing us to the risk of such diseases.You could check here for more info

    ReplyDelete
  18. That is why you need health insurance coverage. You can find the best policy today by getting a health insurance quote.essential oils for hemorrhoids

    ReplyDelete
  19. great you are talking about dangers of night woriking. at night you should sleep!!! - sytropinbooster

    ReplyDelete
  20. What a slick and exact article. The utilization of words is exemplary.http://hcgsite.weebly.com

    ReplyDelete
  21. Healthy habits are an automatic defense against most illnesses and can provide us a long, healthy and thus happy life. MyHealth Streetsville

    ReplyDelete
  22. Amazingly composed blog that has transfixed its crowd.
    read more at this website

    ReplyDelete
  23. I understand that completely because what we stereotype as a salesperson is the fast talker in the cheap suit. Somebody that will say anything to get you to buy what they have just so they can get what they want. That is the furthest thing from what a professional salesperson does. free sample prescriptions

    ReplyDelete
  24. Influential is all that is in this blog.
    here

    ReplyDelete
  25. This comment has been removed by the author.

    ReplyDelete
  26. Planned rehabilitation strategies, can help to ensure safe return to work for employees who have been absent from work due to ill-health or injury.Buy Vitamin K2 Powder

    ReplyDelete
  27. There are a few vitamins, supplements and minerals which are essential for the smooth working of body and can not be made by body itself. www.testogen-reviews.net

    ReplyDelete
  28. Unfortunately, insurance companies are driven by profits, not people (albeit they need people to make profits). If the insurance company can find a legal reason not to pay a claim, chances are they will find it, and you the consumer will suffer. guarantor

    ReplyDelete
  29. I admire this article for the well-researched content and excellent wording. I got so involved in this material that I couldn’t stop reading. I am impressed with your work and skill. Thank you so much. online pills canadian pharmacy

    ReplyDelete
  30. The blog is like an ocean, I wish to drown in.
    Tanoholic

    ReplyDelete
  31. Nice Informative Blog having nice sharing.. see it here

    ReplyDelete
  32. Interesting read
    I think limiting out exposure to the enviromental factor and living a healthy lifestyle can help.
    https://empoweringgoals.com/Isagenix-Cleanse-For-Life

    ReplyDelete
  33. The most notable feature about this blog is how it does not fail to keep its audience engaged at every point.
    cushions

    ReplyDelete
  34. One of the first and most important aspects in any business is to respect the client. If you want to create built in wardrobes in your home, you have to get in touch with the wardrobe Sydney region manufacturers that will uphold your wishes.

    https://readarticles.livejournal.com/626386.html

    ReplyDelete
  35. There are many important aspects that you need to pay attention to when you look for the right team of emergency glass repair Camden specialists. It would be recommended that you only work with emergency glass repair Macarthur experts that have a lot of experience in this field.

    https://readarticles.livejournal.com/655138.html

    ReplyDelete
  36. Cool stuff you have and you keep overhaul every one of us
    does booty pop actually work

    ReplyDelete
  37. I would like to thank you for the efforts you have made in writing this article. I am hoping the same best work from you in the future as well..
    best multivitamin for bodybuilding

    ReplyDelete
  38. Hello I am so delighted I located your blog, I really located you by mistake, while I was watching on google for something else, Anyways I am here now and could just like to say thank for a tremendous post and a all round entertaining website. Please do keep up the great work. Health

    ReplyDelete
  39. Interesting topic for a blog. I have been searching the Internet for fun and came upon your website. Fabulous post. Thanks a ton for sharing your knowledge! It is great to see that some people still put in an effort into managing their websites. I'll be sure to check back again real soon. Check this out

    ReplyDelete
  40. If you have never even thought about collaborating with a China Valve Manufacturer, you should be aware of the many advantages that you have been missing out on. When you need a China Valve, regardless of the exact type, it is recommended that you look for a reputed Chinese manufacturer that can meet your specific requirements.

    http://sarah-blog.over-blog.com/2019/06/benefits-associated-with-a-china-valve-manufacturer.html

    ReplyDelete
  41. Dental veneers are commonly used by dentists these days to cover the front surface of the tooth in order to hide a flaw. Veneers are known as artificial tooth coverings and the most popular ones are veneer and composite. If you would like to beautify your smile with the help of Dental Veneers in Los Angeles the first thing you should do is find a dentist you trust, one that is a member of the American Academy of Cosmetic Dentistry. Root canal infections are painful and you should address them immediately with the help of Root canal dentist los angeles.

    https://presshereandnow.livejournal.com/2304988.html

    ReplyDelete
  42. This article is very nice and Helpful .. Update continued and success is always yes Gan

    Poker99
    DominoQQ
    Capsa Susun
    Poker Uang Asli
    Judi Poker
    Agen Domino

    ReplyDelete
  43. The sooner you realize the importance of white label SEO, the better. This way, you will consider investing in top notch white label SEO services and forget about the alternative, which will not bring any amazing results. A regular SEO approach is something you have to avoid if you want to succeed.

    http://sarah-blog.over-blog.com/2019/08/benefiting-from-the-best-white-label-seo-services.html

    ReplyDelete
  44. Are you in the market for new floors or have grown tired of traditional walling? First and foremost, you should set a budget, even before you begin your search. While you considering the budget, do not forget about underlayment, for this can and often does impact the performance of your new floors. At present there is a high demand for cork underlayment, why because it can add to the feel and longevity of the floor. Furthermore, numerous people choose cork wall tiles for its properties and ability to create a unique décor.

    https://presshereandnow.livejournal.com/2326179.html

    ReplyDelete
  45. Online calculator to convert money and currency using today exchange rate.
    if you want more just look here "convert money"

    ReplyDelete
  46. Zvernec Island in Vlora, Albania is so picturesque. If you are traveling with your family than it is perfect.

    if you want more just look here "Albanian Islands"

    ReplyDelete
  47. Nuestra agencia de Detectives en Sevilla ofrece servicios de investigación privada en cualquier ámbito. Tenemos un despacho de detectives en Sevilla, que además pertenece a una de las mayores agencias de detectives del país, pertenecemos a Grupo Arga Detectives.

    if you want more just look here "Detectives privados Sevilla"

    ReplyDelete
  48. If you have never been on a Dominican Republic Sex Vacation but have always wondered what it would be like to take advantage of this possibility, then you’re going to find out why you don’t want to wait any longer. After enjoying this type of experience, you will probably want to go on Adult Sex Vacations all the time.

    http://emilysloane.over-blog.com/2019/11/should-you-go-on-a-dominican-republic-sex-vacation.html

    ReplyDelete
  49. In many cases, the best part of parties are the decorations and there is nothing more enjoyable than choosing among Luftballons and supplies and creating the amazing décor the event deserves. Whenever a special event is coming up, organizers need to find great ideas on how to decorate the venue and how to make sure everyone has a great time. Since there are many types of balloons and helium ones are among the most popular, shops offer the possibility to helium kaufen to have extra at all times.

    https://presshereandnow.livejournal.com/2347686.html

    ReplyDelete
  50. At first, you might believe that this question is just silly because you usually just post ads in the local paper or on a website where you can find classifieds for just about anything. Well, when it comes to finding ideal candidates for IT jobs such as project manager jobs Sydney, it would be best to benefit from a better recruitment option.

    http://sarah-blog.over-blog.com/2019/11/how-can-you-find-candidates-for-it-jobs.html

    ReplyDelete
  51. The Arga Detective Agency has been for many years,
    developing research as detectives in the field of the community of Madrid, nationally and internationally. Our experience and recognition guarantee us as the most prestigious Detective Agency in Spain

    if you want more just look here "mystery shopping barcelona"

    ReplyDelete
  52. We remind you that the consultation is always free. A qualified professional will gladly assist you and guide you throughout the process. Benefit from our great prices of computer experts in Madrid at the best quality.

    if you want more just look here "Perito informático"

    ReplyDelete
  53. All K managers are composed of 20 managers who work and are high-quality educated managers. It is a place full of uniqueness differentiated from other companies. From the thoughts and perspectives of your customers, K's business trip massage
    Because it is an operational strategy, the satisfaction of managers is high, so if you believe and call me, thank you

    if you want more just look here "Ulsan Branch Massage"

    ReplyDelete
  54. A leading online gambling website, UFA affiliated with another website that is equivalent to a gambling website. That serves like a relative And is by your side 24 hours a day, making you feel safe and free from worry about fraud And also providing a full range of online gambling services, including lotteries, boxing, football betting, playing fish shooting games Play online baccarat Play online casino slots games which have high standards.

    if you want more just look here "UFA888"

    ReplyDelete
  55. As experienced language service providers we are one of the established translation agencies in Germany. For over 30 years our customers have been benefiting from our professionalism and our high standards of quality in the fields of translation and interpreting.

    if you want more just look here "speak"

    ReplyDelete
  56. Now a day, people are very much health conscious. They want to live a happy and healthy life. For that reason, we always keep searching the best way and elements that help them to live a healthy life. Health oils are one of those

    if you want more just look here "https://sellcbdoilonline.blogspot.com/"

    ReplyDelete
  57. Nothing ruins your garden or yard like weeds, those uninvited guests who rob your plants of space and nutrients. So kill the weeds that are the worst, but without harmful chemicals that you can take care of too.

    if you want more just look here "Unkraut"

    ReplyDelete
  58. Looker is a data-discovery app that provides innovative data exploration functionalities for businesses both large and small. With it, they can access a web-based interface where they can easily get real-time insights on their operations via data analytics.

    if you want more just look here "Looker training"

    ReplyDelete
  59. eVisa India (electronic India Visa, which has the same privileges as Indian Visa) is valid only on the following designated Airports and Seaports for entering India. In other words, not all airports and seaports allow entry into India on eVisa India. As a passenger the onus is on you to make sure that your itinerary allows use of this electronic India Visa. If you are entering India form a land border, for instance, then this electronic India Visa (eVisa India) is not suitable for your journey.

    if you want more just look here "indiskt visum"

    ReplyDelete
  60. Easily accessible by communication devices, both smartphones and computers. Access anywhere, anytime There are casino games to choose from, including fish shooting games, table games such as online slots, Pussy888, roulette or card games such as baccarat (baccarat) and many other games with special promotions, free credit. And so on

    if you want more just look here "pussy888"

    ReplyDelete
  61. Wow Such a Nice Blog.I am highly Satisfied with your blog and waiting for the other blog so that I can read all the posts and get some knowledge. pakistan e visa has situated some flights. kenya passport photo requirementsMost of the scheduled international flights have reopened operations as well. Here is a guide about visa Information

    ReplyDelete
  62. We don't publish fake deals or offers that don't work. We only publish real, working coupon codes. We are honest and authentic and shoppers love us for it.

    if you want more just look here "function of beauty coupon"

    ReplyDelete
  63. Natural Crystal Pens, Manifestation Tools, Affirmation, and Law of Attraction driven products.

    if you want more just look here "metaphysical"

    ReplyDelete

  64. Thanks a lot for sharing such a wealth of information! So appreciate ways you have shared to do this with the good guidelines.The foreign travelers who want to travel in South Africa and want to get the visa South Africa by submitting the online documents and filling the visa application form and visiting the places.South Africa is a tourist destination and the industry accounts for a substantial amount of the country's revenue. Burma is a must-see for travelers who like Buddha and beaches, though not necessarily in that order. The country contains thousands of memorable places applied to the by Burma visa application details.

    ReplyDelete
  65. I am satisfied that you just shared this useful information with us. Thanks for sharing wonderful information with us.
    Thank you for this more useful info. Apply for India visa to travel to Indian for tourism and business. Travelers around the world who wish to travel to Vietnam should have apply for Vietnam evisa. If they do not have one, they can apply for a Vietnam e visa online . The online platform offers the fast, secure visa services online. All the information about visa requirements to travel to Vietnam is available.

    ReplyDelete

  66. I have thoroughly enjoyed reading your points and have come to the conclusion that you are right about many of them. Thanks for the post, India conference visa are given for workshops held in India to discuss a particular subject or for international seminars or conferences with the valid evisa details. This is a guide that talks about a evisa Japan and how you can get one with the valid documents of evisa application of online results.

    ReplyDelete
  67. Our Frenchie clothing are always made with organic hypoallergenic materials because French Bulldogs have allergies and sensitivities. Our Frenchie Bluenjy deserves the best and so is yours. Give your French Bulldog health conscious pet products made by an ethical brand.

    if you want more just look here "French Bulldog"

    ReplyDelete
  68. I really appreciate this post and I like this very much. I am waiting for a new post here and Please keep it up in future.. This online system visa extension india enables the travelers to have their visas extended with the online guide by valid documents. All foreign visitors can extend their visas through the frro India visa extension with the online guide and get the visa within days.

    ReplyDelete
  69. What are the best sugar daddy websites for sugar babies finding a sugar daddy? What are the best sugar daddy sites for helping to get a sugar daddy free of charge? If you have asked questions like these, then you have come to the right place.

    dating sites sugar daddy

    ReplyDelete
  70. The secret law of attraction dates back 5,000 years ago and it a natural law. It is not magic, but like magic and prays it is placing an intention to God or Universe to let them know what you want or need. It is a very powerful tool to change your life. You can bring yourself into perfect alignment with what you want or need. With the power of affirmations, visualization, and prays you to improve your life. fastest manifestation technique

    ReplyDelete


  71. Hi, its nice post concerning media print, we all understand media is a enormous source of information.

    Feel free to surf to my web blog ... 풀싸롱

    (freaky)

    ReplyDelete
  72. आपके द्वारा दी गई जानकारी बहुत ही लाभदायक है. जाने uttarakhand ration card list के बारे मे कम्पलीट जानकारी और आसानी से डाउनलोड करें उत्तराखंड राशन कार्ड सूचि 2021

    ReplyDelete
  73. your post is very useful and informative. thanks.. ceo haryana voter list

    ReplyDelete
  74. Medicare supplement insurance plans can be quite confusing, it is generally a good idea to deal with someone who specializes in health insurance with an emphasis on Medicare issues. medicare insurance brokers near me

    ReplyDelete

Note: Only a member of this blog may post a comment.