Thursday, July 4, 2013

The Hazards of Working Nights: for breasts and beyond


The jury is still out whether Angelina's choice is brave or fearful, but the fact remains: having or not having the "bad" genes is not enough to develop or avoid developing breast cancer. As a matter of fact, only 5% to 10% of breast cancer cases result directly from inherited gene defects. Check it yourself, by using this decision tool developed in Stanford.  Even though for members of some families with BRCA mutations the risk may be as high as 80%, this could be because of environmental exposures and behavioral habits "running in the family". What are they?

Among the controllable risk factors are hormone therapy, birth control pills, drugs (like DES discontinued in the 70s), the use of alcohol (if 2 or more drinks per day), heavy smoking since early age, gaining weight after menopause, exercising less than 1-2 hours per week,  certain cosmetics and personal care products, pesticides (such as DDE), PCBs (polychlorinated biphenyls) and other environmental exposures.


One of such exposures is working at night. And Kristan Aronson's team from Queen's University showed that the risk is not limited to nurses, as in most previous studies.


The study examined over 1000 breast cancer cases vs about the same number of healthy cases, matched by age in Vancouver, British Columbia and Kingston, Ontario.  It found that breast cancer risk was twice higher with 30-plus years of night-shift work versus people that did not have night-shift jobs. The risk is more than three times higher for those working at nights in the health care field. But people working at nights or having rotating schedules for shorter duration of time seem to be unaffected.

Why would staying awake after dark for many years be hazardous to health? Perhaps because of the lack of Melatonin. This hormone is produced naturally by our brains when lights go out, to make us less alert and prepare us for sleep. The more daylight exposure versus night time darkness, the better. Melatonin might help the body in many different ways - for example, by downregulating some of the hormones influencing tumor growth or by exhibiting anti-oxidant and immuno-enhancing properties.
Night shifts are also associated with increased stress and a plethora of health conditions as seen from the number of sick leaves people take, periodontal index (measure of oral health), glucose tolerance, number of heart attacks and strokes, cases of IBS and internal cancers. Actually, night time work was shown to increase the risk of cancers even more than exposure to exhaust fumes.

But this is all statistics. Individual cases can certainly break the mold. Yet, it's summer, so let's make the most of natural light.

REFERENCES

Grundy A, Richardson H, Burstyn I, Lohrisch C, Sengupta SK, Lai AS, Lee D, Spinelli JJ, & Aronson KJ (2013). Increased risk of breast cancer associated with long-term shift work in Canada. Occupational and environmental medicine PMID: 23817841

Hansen J, Lassen CF Nested case-control study of night shift work and breast cancer risk among women in the Danish military Occup Environ Med 2012; DOI: 10.1136/oemed-2011-100240.

M S Wolff and A Weston. Breast cancer risk and environmental exposures. Environ Health Perspect. 1997 June; 105(Suppl 4): 891–896. PMCID: PMC1470027

Madigan MP, Ziegler RG, Benichou J, Byrne C, Hoover RN. Proportion of breast cancer cases in the United States explained by well-established risk factors. J Natl Cancer Inst. 1995 Nov 15;87(22):1681–1685.

27 comments:

  1. Just as one international college student with a scholarship grant I seriously could not have the funds for to hire a high-end writing services to post must write my essay for me in my opinion. Additionally the particular terrible ordeals regarding most of the guy students having a few web-sites were being deterrents. However last but not least I ran across this glorious services inside spending budget.

    ReplyDelete
  2. Among the controllable risk factors are hormone therapy, birth control pills, drugs (like DES discontinued in the 70s), the use of alcohol (if 2 or more drinks per day), heavy smoking since early age, gaining weight after menopause, exercising less than 1-2 hours per week, http://findmybud.com/

    ReplyDelete
  3. good is not available formally on Google Play store. mobdro ios the ability to find Mobdro on Google Play Store. best.

    ReplyDelete
  4. good that would certainly have given us access tutu app download Tutu application for android most likely to the TuTu app best.

    ReplyDelete
  5. Naturally supports a woman's health needs by replenishing your body's "good" bacteria to help you feel and live comfortably while acting as a natural yeast infection treatment . women health's website

    ReplyDelete
  6. All For One Home Health Care Inc. is a team of health care professionals who make your home an alternative to a hospital or nursing home stay. iv therapy

    ReplyDelete
  7. Trichophytic closure is a special technique used for the closure of the donor area. Using the technique makes the scar almost invisible and even aids the growth of hair from scar. This helps the surgeon to achieve a better aesthetic outcome of the surgery. Such an advanced technique is difficult to perfect and Dr.YV Rao has mastered it.
    recedinghairline.us

    ReplyDelete
  8. Some universities or colleges may have insurance plan offered to students. These insurance may not answer all your needs but you need to be meticulously considered it. www.smarthealthadvice.com

    ReplyDelete
  9. Many of the elderly have chronic conditions that overwhelm their daily activities or they get diseases repeatedly, which ultimately raises health insurance premiums.Smart Medigap Plans

    ReplyDelete
  10. A specialist was not only there to treat a patient, he was intended to help him remain healthy. Excessively numerous lights outside the house implied awful business for the specialist. urgent care near me

    ReplyDelete
  11. Neuropathy doesn't have to leave you in pain and dissatisfied with life. Taking control of your condition can be difficult, but it is worth it. Neuropathy treatments include: Types of neuropathy

    ReplyDelete
  12. In this day and age, when the worry of present day way of life is producing a bigger number of patients than effective people it is difficult to discover or distinguish where might you get great healthcare administrations. fungus key pro

    ReplyDelete
  13. The Hazards of Working Nights: for breasts and beyond nice title and post Expert Love Solution

    ReplyDelete
  14. But people working at nights or having rotating schedules for shorter duration of time seem to be unaffected.secondary focal hyperhidrosis

    ReplyDelete
  15. However, they will likewise be delighted to hear that herpes can be treated and controlled. mylastoutbreak.com

    ReplyDelete
  16. Angelina's choice is brave or fearful, but the fact remains: having or not having the "bad" genes is not enough to develop or avoid developing breast cancer. best posture corrector

    ReplyDelete
  17. The good cholesterol protect us from heart disease and stroke while the bad cholesterol does the exact opposite of exposing us to the risk of such diseases.You could check here for more info

    ReplyDelete
  18. That is why you need health insurance coverage. You can find the best policy today by getting a health insurance quote.essential oils for hemorrhoids

    ReplyDelete
  19. great you are talking about dangers of night woriking. at night you should sleep!!! - sytropinbooster

    ReplyDelete
  20. What a slick and exact article. The utilization of words is exemplary.http://hcgsite.weebly.com

    ReplyDelete
  21. Healthy habits are an automatic defense against most illnesses and can provide us a long, healthy and thus happy life. MyHealth Streetsville

    ReplyDelete
  22. Amazingly composed blog that has transfixed its crowd.
    read more at this website

    ReplyDelete
  23. I understand that completely because what we stereotype as a salesperson is the fast talker in the cheap suit. Somebody that will say anything to get you to buy what they have just so they can get what they want. That is the furthest thing from what a professional salesperson does. free sample prescriptions

    ReplyDelete
  24. Influential is all that is in this blog.
    here

    ReplyDelete
  25. This comment has been removed by the author.

    ReplyDelete
  26. Planned rehabilitation strategies, can help to ensure safe return to work for employees who have been absent from work due to ill-health or injury.Buy Vitamin K2 Powder

    ReplyDelete
  27. There are a few vitamins, supplements and minerals which are essential for the smooth working of body and can not be made by body itself. www.testogen-reviews.net

    ReplyDelete